Recombinant Anti-ABCC1 Vesicular Antibody, EV Displayed (VS-0425-YC633)
CAT#: VS-0425-YC633
The Recombinant Anti-ABCC1 Vesicular Antibody, EV Displayed (VS-0425-YC633) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ABCC1-expressed cells or tissues. ABCC1 is an ABC transporter associated with multidrug resistance, transporting various substrates like glucuronides and bile salts.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2380/if_selected.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ABCC1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- ATP binding cassette subfamily C member 1
- Biological Process
- Lipid transport, Transport
- Molecular Function
- Hydrolase, Translocase
- Cellular Localization
- Plasma membrane, Cell Junctions
- Introduction
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
- Alternative Names
- GS-X, MRP, MRP1
- Gene ID
- 4363
- UniProt ID
- P33527
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Datasheet
MSDS
COA
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See other products for "ABCC1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-23 | Recombinant Anti-human ABCC1 Antibody | WB, IP, FuncS | IgG |
| MHH-23 | Recombinant Human Anti-human ABCC1 Antibody | WB, FC, FuncS | IgG |
| MOB-0916MZ | Mouse Anti-ABCC1 Recombinant Antibody (clone NSQn6) | FC, IHC-Fr, IHC-P, WB | Mouse IgG2a |
| HPAB-0108CQ | Human Anti-ABCC1 Recombinant Antibody (clone A5) | ELISA, FC, FuncS | Human IgG1 |
| MRO-1024-CN | Rabbit Anti-ABCC1 Recombinant Antibody (clone JA93-03) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-23-F(E) | Recombinant Anti-human ABCC1 Antibody Fab Fragment | FC, IP, FuncS | Fab |
| MHH-23-F(E) | Recombinant Human Anti-human ABCC1 Antibody Fab Fragment | WB, IHC, FuncS | Fab |
| HPAB-0108CQ-F(E) | Human Anti-ABCC1 Recombinant Antibody (clone A5); Fab Fragment | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-23-S(P) | Recombinant Anti-human ABCC1 Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| MHH-23-S(P) | Recombinant Human Anti-human ABCC1 Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0011 | Hi-Affi™ Rabbit Anti-ABCC1 Recombinant Antibody (clone DS11AB) | FC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0673LC | Rat Anti-ABCC1 Recombinant Antibody (clone MRPr1) | ELISA | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY21 | Anti-ABCC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY22 | Anti-Mouse ABCC1 Immunohistochemistry Kit | IHC |
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