Recombinant Anti-ADAM15 Vesicular Antibody, EV Displayed (VS-0425-YC361) (CAT#: VS-0425-YC361)

The Recombinant Anti-ADAM15 Vesicular Antibody, EV Displayed (VS-0425-YC361) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ADAM15-expressed cells or tissues. The ADAM15 is an ADAM protein involved in adhesion and signaling, interacting with integrins and Src family kinases.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • ADAM15
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • ADAM metallopeptidase domain 15
  • Biological Process
  • Angiogenesis, Cell adhesion, Collagen degradation
  • Molecular Function
  • Hydrolase, Metalloprotease, Protease
  • Cellular Localization
  • Vesicles
  • Introduction
  • The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
  • Alternative Names
  • MDC15

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ADAM15"

Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products Fab Antibody Products ScFv Antibody Products Mouse Antibody Products Rabbit Monoclonal Antibody Products

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for VS-0425-YC361. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Go to compare

Go to compare