Recombinant Anti-ADGRE1 Vesicular Antibody, EV Displayed (VS-0425-YC707)

CAT#: VS-0425-YC707

The Recombinant Anti-ADGRE1 Vesicular Antibody, EV Displayed (VS-0425-YC707) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ADGRE1-expressed cells or tissues. ADGRE1 is a G protein-coupled receptor involved in adenylate cyclase signaling, expressed in diverse tissues, with an ortholog in humans.

Gene Expression
Figure 1 Colon Figure 2 Bone marrow Figure 3 RNA cell line category: Cell line enhanced (A549, BJ hTERT+, GAMG, HDLM-2, HMC-1, Karpas-707)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • ADGRE1
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Mouse
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Adhesion G protein-coupled receptor E1
  • Biological Process
  • Adaptive immunity, Immunity
  • Molecular Function
  • G-protein coupled receptor, Receptor, Transducer
  • Introduction
  • Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; intestine; and liver. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1).
  • Alternative Names
  • DD7A5-7, EGF-TM7, Emr1, F4/80, Gpf480, Ly71, TM7LN3
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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