Recombinant Anti-ADGRE2 Vesicular Antibody, EV Displayed (VS-0425-YC586)
CAT#: VS-0425-YC586
The Recombinant Anti-ADGRE2 Vesicular Antibody, EV Displayed (VS-0425-YC586) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ADGRE2-expressed cells or tissues. ADGRE2 is a G-protein coupled receptor primarily expressed in myeloid cells, promoting cell adhesion.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55200/881_B6_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HEL, HMC-1, NB-4, RPMI-8226, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127507-ADGRE2
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ADGRE2
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Adhesion G protein-coupled receptor E2
- Biological Process
- Cell adhesion, Inflammatory response
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles, Cytosol
- Introduction
- This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
- Alternative Names
- CD312, EMR2
- Gene ID
- 30817
- UniProt ID
- Q9UHX3
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281-WJ | Mouse Anti-ADGRE2 Recombinant Antibody (clone SC93.15) | ELISA, FC | Human IgG |
| HPAB-0282-WJ | Mouse Anti-ADGRE2 Recombinant Antibody (clone SC93.15.1) | ELISA, FC | Human IgG |
| HPAB-0283-WJ | Human Anti-ADGRE2 Recombinant Antibody (clone hSC93.253) | ELISA, FC, FuncS | Humanized IgG |
| HPAB-0284-WJ | Human Anti-ADGRE2 Recombinant Antibody (clone hSC93.256) | ELISA, FC, FuncS | Humanized IgG |
| VS-0723-WK153 | Human Anti-ADGRE2 Recombinant Antibody (VS-0723-WK153) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281-WJ-S(P) | Mouse Anti-ADGRE2 Recombinant Antibody (clone SC93.15); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0282-WJ-S(P) | Mouse Anti-ADGRE2 Recombinant Antibody (clone SC93.15.1); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0283-WJ-S(P) | Human Anti-ADGRE2 Recombinant Antibody (clone hSC93.253); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0284-WJ-S(P) | Human Anti-ADGRE2 Recombinant Antibody (clone hSC93.256); scFv Fragment | ELISA, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281-WJ-F(E) | Mouse Anti-ADGRE2 Recombinant Antibody (clone SC93.15); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0282-WJ-F(E) | Mouse Anti-ADGRE2 Recombinant Antibody (clone SC93.15.1); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0283-WJ-F(E) | Human Anti-ADGRE2 Recombinant Antibody (clone hSC93.253); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0284-WJ-F(E) | Human Anti-ADGRE2 Recombinant Antibody (clone hSC93.256); Fab Fragment | ELISA, FC | Humanized Fab |
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