Recombinant Anti-ART4 Vesicular Antibody, EV Displayed (VS-0425-YC737)
CAT#: VS-0425-YC737
The Recombinant Anti-ART4 Vesicular Antibody, EV Displayed (VS-0425-YC737) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ART4-expressed cells or tissues. ART4 is a protein with an ART motif, linked to the Dombrock blood group and ADP-ribosyltransferase family. It has variants leading to adverse transfusion reactions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to rods & rings.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/75664/1762_G4_5_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (AN3-CA, HEL, Hep G2, HUVEC TERT2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111339-ART4
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ART4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
- Molecular Function
- Blood group antigen, Glycosyltransferase, Nucleotidyltransferase, Transferase
- Cellular Localization
- Rods & Rings
- Introduction
- This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known.
- Alternative Names
- ARTC4, CD297, DO, DOK1
- Gene ID
- 420
- UniProt ID
- Q93070
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Datasheet
MSDS
COA
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See other products for "ART4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2103z | Recombinant Anti-Human ART4 Antibody | ELISA, WB, IF, FuncS | IgG |
| FAMAB-1001CQ | Human Anti-ART4 Recombinant Antibody (clone Mima-143) | ELISA | Human IgG1 |
| FAMAB-1002CQ | Human Anti-ART4 Recombinant Antibody (clone Mima-73) | FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2103z-F(E) | Recombinant Anti-Human ART4 Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2103z-S(P) | Recombinant Anti-Human ART4 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
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