Recombinant Anti-CCRL2 Vesicular Antibody, EV Displayed (VS-0425-YC691)
CAT#: VS-0425-YC691
The Recombinant Anti-CCRL2 Vesicular Antibody, EV Displayed (VS-0425-YC691) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CCRL2-expressed cells or tissues. CCRL2 enables chemokine receptor activity, involved in inflammatory responses, located in plasma membranes and expressed in systems including the central nervous system.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_A_7_8.jpg
Normal Tissue
Figure 7 Spleen
Cells in red pulp Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43238/93570_B_8_4.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HEL, OE19, PC-3, RT4, TIME, U-266/84)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000121797-CCRL2
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CCRL2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-C motif chemokine receptor like 2
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- Enables chemokine receptor binding activity. Involved in inflammatory response. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm and external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Orthologous to human CCRL2 (C-C motif chemokine receptor like 2).
- Alternative Names
- 1810047I05Rik, Ackr5, CCR11, Cmkbr1l2, E01, L-CCR
- Gene ID
- 54199
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Datasheet
MSDS
COA
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See other products for "CCRL2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0378CT | Mouse Anti-CCRL2 Recombinant Antibody (clone NN0269-6B26) | FC | Mouse IgG2 |
| FAMAB-1583CQ | Mouse Anti-CCRL2 Recombinant Antibody (clone BZ5B8) | FuncS, ICC, IP, WB, ELISA, FC, IHC | Mouse IgG2a |
| FAMAB-1584CQ | Mouse Anti-CCRL2 Recombinant Antibody (clone BZ2E3) | FuncS, ICC, IP, WB, ELISA, FC, IHC | Mouse IgG2a |
| VS7-HM320 | Mouse Anti-CCRL2 Recombinant Antibody (clone 4A5A5) | FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1105 | Anti-Mouse CCRL2 Immunohistochemistry Kit | IHC |
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