Recombinant Anti-CD1C Vesicular Antibody, EV Displayed (VS-0425-YC729) (CAT#: VS-0425-YC729)
The Recombinant Anti-CD1C Vesicular Antibody, EV Displayed (VS-0425-YC729) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD1C-expressed cells or tissues. CD1C is a protein involved in lipid antigen presentation, associated with diseases like Mycobacterium malmoense. It participates in immune system pathways, with CD1B as a significant paralog.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line JURKAT
(Immunofluorescent staining of human cell line JURKAT shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68359/1970_G5_2_selected.jpg
(Immunofluorescent staining of human cell line JURKAT shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68359/1970_G5_2_selected.jpg
Figure 2 RNA cell line category: Group enriched (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000158481-CD1C
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000158481-CD1C
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD1C
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD1c molecule
- Biological Process
- Adaptive immunity, Immunity
- Cellular Localization
- Golgi apparatus, Vesicles, Endoplasmic reticulum
- Introduction
- CD1C (CD1c Molecule) is a Protein Coding gene. Diseases associated with CD1C include Mycobacterium Malmoense and Foramen Magnum Meningioma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include beta-2-microglobulin binding and lipopeptide binding. An important paralog of this gene is CD1B.
- Alternative Names
- CD1
- Gene ID
- 911
- UniProt ID
- P29017
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1419z | Mouse Anti-CD1C Recombinant Antibody (clone 4H11) | IF, IHC, WB | Mouse IgG1 |
| MOB-1732MZ | Mouse Anti-CD1C Recombinant Antibody (clone M272) | FC | Mouse IgG1 |
| FAMAB-1037CQ | Human Anti-CD1C Recombinant Antibody (clone M241) | IP, RIA, IF, IHC | Human IgG1 |
| VS7-HM446 | Mouse Anti-CD1C Recombinant Antibody (clone 3G1B3) | IHC, FCM | Mouse IgG2b |
| VS7-HM447 | Mouse Anti-CD1C Recombinant Antibody (clone 2A7C11) | IHC, FCM | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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