Recombinant Anti-Cd244a Vesicular Antibody, EV Displayed (VS-0425-YC692) (CAT#: VS-0425-YC692)
The Recombinant Anti-Cd244a Vesicular Antibody, EV Displayed (VS-0425-YC692) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Cd244a-expressed cells or tissues. Cd244a enables MHC class I protein binding and is involved in immune responses like dendritic cell and natural killer cell activation, expressed in various tissues.
Specific Inquiry
Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Cd244a
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD244 molecule A
- Biological Process
- Adaptive immunity, Immunity, Innate immunity
- Molecular Function
- Receptor
- Introduction
- Predicted to enable MHC class I protein binding activity. Involved in myeloid dendritic cell activation; natural killer cell activation involved in immune response; and positive regulation of lymphocyte proliferation. Located in external side of plasma membrane. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human CD244 (CD244 molecule).
- Alternative Names
- 2B4, C9.1, Cd244, F730046O15Rik, Ly90, NAIL, NKR2B4, Nmrk, SLAMF4
- Gene ID
- 18106
- UniProt ID
- Q3S4B1
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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