Recombinant Anti-CD69 Vesicular Antibody, EV Displayed (VS-0425-YC179) (CAT#: VS-0425-YC179)
The Recombinant Anti-CD69 Vesicular Antibody, EV Displayed (VS-0425-YC179) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD69-expressed cells or tissues. The CD69 is a protein involved in pathways related to hematopoietic stem cell differentiation, associated with conditions like Coccidioidomycosis.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Appendix
(Lymphoid tissue
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2503/6467_A_2_2.jpg
(Lymphoid tissue
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2503/6467_A_2_2.jpg
Figure 2 Lymph node
(Germinal center cells
Staining:Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50525/147533_A_8_8.jpg
(Germinal center cells
Staining:Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50525/147533_A_8_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (HL-60, JURKAT, K-562, MOLT-4, U-266/70, U-698, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110848-CD69
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110848-CD69
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD69
- Host Animal
- Human
- Antibody Isotype
- IgG4
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 1.84 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD69 molecule
- Introduction
- CD69 (CD69 Molecule) is a Protein Coding gene. Diseases associated with CD69 include Coccidioidomycosis and Asthma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Kit receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include calcium ion binding and carbohydrate binding. An important paralog of this gene is CLEC2A.
- Alternative Names
- CLEC2C
- Gene ID
- 969
- UniProt ID
- Q07108
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1417z | Mouse Anti-CD69 Recombinant Antibody (clone 40B11) | IHC, FC, FuncS | Mouse IgG1 |
| MOB-0359MZ | Recombinant Mouse Anti-Human CD69 Molecule Antibody (clone GN51) | ELISA | Mouse antibody |
| VS3-XY395 | Mouse Anti-CD69 Recombinant Antibody, FITC (clone 4AFN50) | FC, IF | Mouse IgG1 |
| VS3-XY396 | Mouse Anti-CD69 Recombinant Antibody (clone 4AFN50) | FC, IF | Mouse IgG1 |
| VS13-YC172 | Rabbit Anti-CD69 Recombinant Antibody (VS13-YC172) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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