Recombinant Anti-CD84 Vesicular Antibody, EV Displayed (VS-0425-YC172)

CAT#: VS-0425-YC172

The Recombinant Anti-CD84 Vesicular Antibody, EV Displayed (VS-0425-YC172) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD84-expressed cells or tissues. The CD84 is predicted to enable identical protein binding activity and is involved in the regulation of gene expression and macrophage activation.

Gene Expression
Figure 1 IF staining of human cell line HEL Figure 2 Figure 3 Lymph node Figure 4 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, HMC-1, MOLT-4, U-698)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CD84
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Mouse
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CD84 molecule
  • Biological Process
  • Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity
  • Molecular Function
  • Receptor
  • Cellular Localization
  • Plasma membrane, Vesicles
  • Introduction
  • Predicted to enable identical protein binding activity. Involved in regulation of gene expression; regulation of macrophage activation; and regulation of signal transduction. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in brain; embryo; and testis. Orthologous to human CD84 (CD84 molecule).
  • Alternative Names
  • A130013D22Rik, CDw84, SLAMF5
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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