Recombinant Anti-CDH19 Vesicular Antibody, EV Displayed (VS-0425-YC648)
CAT#: VS-0425-YC648
The Recombinant Anti-CDH19 Vesicular Antibody, EV Displayed (VS-0425-YC648) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH19-expressed cells or tissues. CDH19 is a cadherin involved in calcium ion binding, with related pathways like ERK signaling.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human placenta
Immunohistochemical staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56332/ihc_selected.jpg
Normal Tissue
Figure 2 Colon
Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56332/128388_A_9_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56332/128388_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56332/128388_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56332/128388_A_6_6.jpg
Normal Tissue
Figure 6 Placenta
Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56332/128388_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (SK-MEL-30, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000071991-CDH19
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDH19
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cadherin 19
- Biological Process
- Cell adhesion
- Introduction
- CDH19 (Cadherin 19) is a Protein Coding gene. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH7.
- Alternative Names
- CDH7
- Gene ID
- 28513
- UniProt ID
- Q9H159
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0065CQ | Human Anti-CDH19 Recombinant Antibody (HPAB-0065CQ) | FC | Human IgG4 |
| HPAB-0066CQ | Human Anti-CDH19 Recombinant Antibody (HPAB-0066CQ) | FC | Human IgG1 |
| HPAB-0067CQ | Human Anti-CDH19 Recombinant Antibody (HPAB-0067CQ) | FC | Human IgG1 |
| HPAB-0068CQ | Human Anti-CDH19 Recombinant Antibody (HPAB-0068CQ) | FC | Human IgG1 |
| HPAB-0069CQ | Human Anti-CDH19 Recombinant Antibody (HPAB-0069CQ) | FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0065CQ-S(P) | Human Anti-CDH19 Recombinant Antibody; scFv Fragment (HPAB-0065CQ-S(P)) | FC | Human scFv |
| HPAB-0066CQ-S(P) | Human Anti-CDH19 Recombinant Antibody; scFv Fragment (HPAB-0066CQ-S(P)) | FC | Human scFv |
| HPAB-0067CQ-S(P) | Human Anti-CDH19 Recombinant Antibody; scFv Fragment (HPAB-0067CQ-S(P)) | FC | Human scFv |
| HPAB-0068CQ-S(P) | Human Anti-CDH19 Recombinant Antibody; scFv Fragment (HPAB-0068CQ-S(P)) | FC | Human scFv |
| HPAB-0069CQ-S(P) | Human Anti-CDH19 Recombinant Antibody; scFv Fragment (HPAB-0069CQ-S(P)) | FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0065CQ-F(E) | Human Anti-CDH19 Recombinant Antibody; Fab Fragment (HPAB-0065CQ-F(E)) | FC | Human Fab |
| HPAB-0066CQ-F(E) | Human Anti-CDH19 Recombinant Antibody; Fab Fragment (HPAB-0066CQ-F(E)) | FC | Human Fab |
| HPAB-0067CQ-F(E) | Human Anti-CDH19 Recombinant Antibody; Fab Fragment (HPAB-0067CQ-F(E)) | FC | Human Fab |
| HPAB-0068CQ-F(E) | Human Anti-CDH19 Recombinant Antibody; Fab Fragment (HPAB-0068CQ-F(E)) | FC | Human Fab |
| HPAB-0069CQ-F(E) | Human Anti-CDH19 Recombinant Antibody; Fab Fragment (HPAB-0069CQ-F(E)) | FC | Human Fab |
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