Recombinant Anti-CLEC2D Vesicular Antibody, EV Displayed (VS-0425-YC310) (CAT#: VS-0425-YC310)
The Recombinant Anti-CLEC2D Vesicular Antibody, EV Displayed (VS-0425-YC310) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CLEC2D-expressed cells or tissues. The CLEC2D is a C-type lectin family protein inhibiting osteoclast formation, featuring transmembrane and extracellular domains with variant isoforms.

(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47584/747_H3_2_selected.jpg

(Immunohistochemical staining of human colon shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/ihc_selected.jpg

(Immunofluorescent staining of human cell line MCF7 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47584/714_H3_1_blue_red_green.jpg

(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47584/713_H3_2_blue_red_green.jpg

(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_9_3.jpg

(Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_8_5.jpg

(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_4_6.jpg

(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17649/40429_A_7_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000069493-CLEC2D
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CLEC2D
- Host Animal
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-type lectin domain family 2 member D
- Molecular Function
- Receptor
- Cellular Localization
- Golgi apparatus
- Introduction
- This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]
- Alternative Names
- CLAX, LLT1, OCIL
- Gene ID
- 29121
- UniProt ID
- Q9UHP7
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CLEC2D"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0684CL | Mouse Anti-CLEC2D Recombinant Antibody (TAB-0684CL) | FC, ELISA | Mouse IgG1 |
TAB-0685CL | Mouse Anti-CLEC2D Recombinant Antibody (TAB-0685CL) | FC, ELISA | Mouse IgG1 |
TAB-0684CL-S(P) | Mouse Anti-CLEC2D Recombinant Antibody; scFv Fragment (TAB-0684CL-S(P)) | FC, ELISA | Mouse scFv |
TAB-0684CL-F(E) | Mouse Anti-CLEC2D Recombinant Antibody; Fab Fragment (TAB-0684CL-F(E)) | FC, ELISA | Mouse Fab |
TAB-0685CL-F(E) | Mouse Anti-CLEC2D Recombinant Antibody; Fab Fragment (TAB-0685CL-F(E)) | FC, ELISA | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0425-YC310. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, WB, BLI, SPR
Application: ELISA, WB, BLI, SPR
Application: ELISA, FC, WB, Block
Application: ELISA, FC
Application: WB, IHC, ELISA, FC
Application: ELISA, WB
Application: ELISA, IHC, WB
Application: ELISA, Activ, Block
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.