Recombinant Anti-CLEC5A Vesicular Antibody, EV Displayed (VS-0425-YC531)
CAT#: VS-0425-YC531
The Recombinant Anti-CLEC5A Vesicular Antibody, EV Displayed (VS-0425-YC531) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CLEC5A-expressed cells or tissues. CLEC5A is a type II transmembrane protein of the C-type lectin family, involved in cell activation and inflammation. It interacts with dnax-activation protein 12.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line NB-4
Immunofluorescent staining of human cell line NB-4 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54137/1714_B9_3_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HL-60, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000258227-CLEC5A
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CLEC5A
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-type lectin domain containing 5A
- Biological Process
- Host-virus interaction, Immunity, Innate immunity
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Cellular Localization
- Plasma membrane, Cytosol
- Introduction
- This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.
- Alternative Names
- CLECSF5, MDL-1
- Gene ID
- 23601
- UniProt ID
- Q9NY25
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CLEC5A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0309LY | Human Anti-CLEC5A Recombinant Antibody (HPAB-0309LY) | Inhib, FC, ELISA, IP | Human IgG |
| HPAB-0310LY | Human Anti-CLEC5A Recombinant Antibody (HPAB-0310LY) | Inhib, FC, ELISA, IP | Human IgG |
| HPAB-0311LY | Human Anti-CLEC5A Recombinant Antibody (HPAB-0311LY) | Inhib, FC, ELISA, IP | Human IgG |
| HPAB-0312LY | Human Anti-CLEC5A Recombinant Antibody (HPAB-0312LY) | Inhib, FC, ELISA, IP | Human IgG |
| HPAB-0313LY | Human Anti-CLEC5A Recombinant Antibody (HPAB-0313LY) | Inhib, FC, ELISA, IP | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0309LY-S(P) | Human Anti-CLEC5A Recombinant Antibody; scFv Fragment (HPAB-0309LY-S(P)) | Inhib, FC, ELISA, IP | Human scFv |
| HPAB-0310LY-S(P) | Human Anti-CLEC5A Recombinant Antibody; scFv Fragment (HPAB-0310LY-S(P)) | Inhib, FC, ELISA, IP | Human scFv |
| HPAB-0311LY-S(P) | Human Anti-CLEC5A Recombinant Antibody; scFv Fragment (HPAB-0311LY-S(P)) | Inhib, FC, ELISA, IP | Human scFv |
| HPAB-0312LY-S(P) | Human Anti-CLEC5A Recombinant Antibody; scFv Fragment (HPAB-0312LY-S(P)) | Inhib, FC, ELISA, IP | Human scFv |
| HPAB-0962-FY-F(E) | Mouse Anti-CLEC5A Recombinant Antibody; Fab Fragment (HPAB-0962-FY-F(E)) | ELISA, WB, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0309LY-F(E) | Human Anti-CLEC5A Recombinant Antibody; Fab Fragment (HPAB-0309LY-F(E)) | Inhib, FC, ELISA, IP | Human Fab |
| HPAB-0310LY-F(E) | Human Anti-CLEC5A Recombinant Antibody; Fab Fragment (HPAB-0310LY-F(E)) | Inhib, FC, ELISA, IP | Human Fab |
| HPAB-0311LY-F(E) | Human Anti-CLEC5A Recombinant Antibody; Fab Fragment (HPAB-0311LY-F(E)) | Inhib, FC, ELISA, IP | Human Fab |
| HPAB-0312LY-F(E) | Human Anti-CLEC5A Recombinant Antibody; Fab Fragment (HPAB-0312LY-F(E)) | Inhib, FC, ELISA, IP | Human Fab |
| HPAB-0962-FY-S(P) | Mouse Anti-CLEC5A Recombinant Antibody; scFv Fragment (HPAB-0962-FY-S(P)) | ELISA, WB, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY67 | AbPlus™ Anti-CLEC5A Magnetic Beads (VS-0424-XY67) | IP, Protein Purification |
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