Recombinant Anti-CLEC5A Vesicular Antibody, EV Displayed (VS-0425-YC531) (CAT#: VS-0425-YC531)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CLEC5A

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-type lectin domain containing 5A

• Biological Process
• Host-virus interaction, Immunity, Innate immunity

• Molecular Function
• Host cell receptor for virus entry, Receptor

• Cellular Localization
• Plasma membrane, Cytosol

• Introduction
• This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.

• Alternative Names
• CLECSF5, MDL-1

• Gene ID
• 23601

• UniProt ID
• Q9NY25

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