Recombinant Anti-CMKLR1 Vesicular Antibody, EV Displayed (VS-0425-YC684)
CAT#: VS-0425-YC684
The Recombinant Anti-CMKLR1 Vesicular Antibody, EV Displayed (VS-0425-YC684) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CMKLR1-expressed cells or tissues. CMKLR1 enables hormone and chemokine-like receptor activities, involved in thermogenesis and adipocyte differentiation, having orthologous human proteins.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human kidney
Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in renal tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47865/ihc_selected.jpg
Normal Tissue
Figure 2 Parathyroid gland
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47865/109996_A_3_8.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47865/109996_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47865/109996_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47865/109996_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, hTERT-RPE1, LHCN-M2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174600-CMKLR1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CMKLR1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Chemerin chemokine-like receptor 1
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- Predicted to enable adipokinetic hormone binding activity; adipokinetic hormone receptor activity; and transmembrane signaling receptor activity. Involved in negative regulation of interleukin-12 production; positive regulation of cold-induced thermogenesis; and positive regulation of fat cell differentiation. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; embryo mesenchyme; jaw; lung; and uterus. Orthologous to human CMKLR1 (chemerin chemokine-like receptor 1).
- Alternative Names
- ChemR23, DEZ, Gpcr27, mcmklr1
- Gene ID
- 14747
- UniProt ID
- P97468
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Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Cmklr1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-481CQ | Rat Anti-CMKLR1 Recombinant Antibody (clone CBL372) | Neut, WB | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1733CQ | Mouse Anti-CMKLR1 Recombinant Antibody (clone BZ194) | FuncS, IP, WB, ELISA, FC, IF, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1540 | Anti-Mouse CMKLR1 Immunohistochemistry Kit | IHC |
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