Recombinant Anti-CTCFL Vesicular Antibody, EV Displayed (VS-0425-YC730) (CAT#: VS-0425-YC730)

The Recombinant Anti-CTCFL Vesicular Antibody, EV Displayed (VS-0425-YC730) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CTCFL-expressed cells or tissues. CTCFL is a protein involved in nucleic acid binding, linked to diseases like Spherocytosis Type 4. It functions in DNA transcription regulation with CTCF as a paralog.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CTCFL
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CCCTC-binding factor like
  • Biological Process
  • Cell cycle, Transcription, Transcription regulation
  • Molecular Function
  • Activator, Chromatin regulator, DNA-binding, Repressor
  • Cellular Localization
  • Nucleoplasm, Nuclear bodies, Cytosol
  • Introduction
  • CTCFL (CCCTC-Binding Factor Like) is a Protein Coding gene. Diseases associated with CTCFL include Spherocytosis, Type 4 and Silver-Russell Syndrome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is CTCF.
  • Alternative Names
  • BORIS, CT27, dJ579F20.2

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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