Recombinant Anti-CTCFL Vesicular Antibody, EV Displayed (VS-0425-YC730) (CAT#: VS-0425-YC730)
The Recombinant Anti-CTCFL Vesicular Antibody, EV Displayed (VS-0425-YC730) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CTCFL-expressed cells or tissues. CTCFL is a protein involved in nucleic acid binding, linked to diseases like Spherocytosis Type 4. It functions in DNA transcription regulation with CTCF as a paralog.

(Immunofluorescent staining of human cell line K-562 shows localization to nucleoplasm, nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1472/1854_E5_5_selected.jpg

* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1472/ihc_selected.jpg

* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1472/144129_B_5_3_val_selected.jpg

(Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1472/144129_A_8_3.jpg

(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Pachytene spermatocytes Staining: Low Intensity: Weak Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: Low Intensity: Weak Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1472/144129_A_5_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000124092-CTCFL
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CTCFL
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CCCTC-binding factor like
- Biological Process
- Cell cycle, Transcription, Transcription regulation
- Molecular Function
- Activator, Chromatin regulator, DNA-binding, Repressor
- Cellular Localization
- Nucleoplasm, Nuclear bodies, Cytosol
- Introduction
- CTCFL (CCCTC-Binding Factor Like) is a Protein Coding gene. Diseases associated with CTCFL include Spherocytosis, Type 4 and Silver-Russell Syndrome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is CTCF.
- Alternative Names
- BORIS, CT27, dJ579F20.2
- Gene ID
- 140690
- UniProt ID
- Q8NI51
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CTCFL"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3835z | Mouse Anti-CTCFL Recombinant Antibody (clone 8F4) | WB, IF, ELISA | Mouse IgG1 |
FAMAB-1031CQ | Human Anti-CTCFL Recombinant Antibody (clone 20B11) | ChIP, IP, WB, ELISA, IF, IHC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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