Recombinant Anti-CXADR Vesicular Antibody, EV Displayed (VS-0425-YC283)
CAT#: VS-0425-YC283
The Recombinant Anti-CXADR Vesicular Antibody, EV Displayed (VS-0425-YC283) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CXADR-expressed cells or tissues. The CXADR is a cell adhesion molecule involved in pathways like immune response and is linked to diseases such as myocarditis and cardiomyopathy.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30411/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5103/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human salivary gland
Immunohistochemical staining of human salivary gland shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3342/ihc_selected.jpg
Normal Tissue
Figure 4 Rectum
High expression in rectum
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30411/63345_A_5_3_val_selected.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30411/63345_A_7_4.jpg
Normal Tissue
Figure 6 Testis
Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30411/63345_A_6_6.jpg
Normal Tissue
Figure 7 Skin
Cells in basal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in spinous layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Eccrine glands Staining: Medium Intensity: Moderate Quantity: 75%-25% Endothelial cells Staining: Medium Intensity: Moderate Fibrohistiocytic cells Staining: High Intensity: Strong Hair follicles Staining: Medium Intensity: Moderate Quantity:>75% Langerhans cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30411/63345_B_8_1.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (CACO-2, Hep G2, NTERA-2, RT4)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154639-CXADR
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CXADR
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CXADR Ig-like cell adhesion molecule
- Biological Process
- Cell adhesion, Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor
- Cellular Localization
- Plasma membrane, Cell Junctions, Nucleoplasm
- Introduction
- CXADR (CXADR, Ig-Like Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with CXADR include Myocarditis and Dilated Cardiomyopathy. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding and integrin binding. An important paralog of this gene is ENSG00000277666.
- Alternative Names
- CAR
- Gene ID
- 1525
- UniProt ID
- P78310
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Datasheet
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COA
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See other products for "CXADR"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2024z | Mouse Anti-CXADR Recombinant Antibody (clone 33A2) | WB, ICC, IF, IHC | Mouse IgG1 |
| MOB-0719MZ | Recombinant Mouse Anti-Human CXADR Antibody (clone 3U7) | ICC | Mouse antibody |
| VS-0723-WK60 | Human Anti-CXADR Recombinant Antibody (VS-0723-WK60) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-095MZ | Mouse Anti-CXADR Recombinant Antibody (TAB-095MZ) | WB, FC, FuncS | Mouse IgG2a, κ |
| TAB-096MZ | Mouse Anti-CXADR Recombinant Antibody (TAB-096MZ) | FuncS | Mouse IgG2b, κ |
| TAB-095MZ-S(P) | Mouse Anti-CXADR Recombinant Antibody; scFv Fragment (TAB-095MZ-S(P)) | FC | Mouse scFv |
| TAB-095MZ-F(E) | Mouse Anti-CXADR Recombinant Antibody; Fab Fragment (TAB-095MZ-F(E)) | FC | Mouse Fab |
| TAB-096MZ-F(E) | Mouse Anti-CXADR Recombinant Antibody; Fab Fragment (TAB-096MZ-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0865MZ | Chicken Anti-CAR Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4124 | Hi-Affi™ Rabbit Anti-CXADR Recombinant Antibody (clone SI195DS) | FC | Rabbit IgG |
| MOR-4125 | Hi-Affi™ Rabbit Anti-CXADR Recombinant Antibody (clone SI196DS) | ICC, IF, IF, FC | Rabbit IgG |
| MOR-4126 | Hi-Affi™ Rabbit Anti-Cxadr Recombinant Antibody (clone SI197DS) | ELISA, IHC-P | Rabbit IgG |
| MOR-4127 | Hi-Affi™ Rabbit Anti-CXADR Recombinant Antibody (clone SI198DS) | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1212 | AbPlus™ Anti-CXADR Magnetic Beads (VS-0724-YC1212) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1810 | Anti-Mouse CXADR Immunohistochemistry Kit | IHC |
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