Recombinant Anti-DCSTAMP Vesicular Antibody, EV Displayed (VS-0425-YC226)

CAT#: VS-0425-YC226

The Recombinant Anti-DCSTAMP Vesicular Antibody, EV Displayed (VS-0425-YC226) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to DCSTAMP-expressed cells or tissues. The DCSTAMP is a seven-pass transmembrane protein involved in immunological functions in dendritic cells, playing a role in osteoclastogenesis.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (U-87 MG)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • DCSTAMP
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Dendrocyte expressed seven transmembrane protein
  • Biological Process
  • Differentiation, Immunity
  • Introduction
  • This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
  • Alternative Names
  • DC-STAMP, FIND, TM7SF4
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