Recombinant Anti-GABRR1 Vesicular Antibody, EV Displayed (VS-0425-YC738)
CAT#: VS-0425-YC738
The Recombinant Anti-GABRR1 Vesicular Antibody, EV Displayed (VS-0425-YC738) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GABRR1-expressed cells or tissues. GABRR1 is a GABA receptor part of the rho subunit family, with multiple transcript variants linked to chloride channel activity.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (NTERA-2, OE19, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146276-GABRR1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GABRR1
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Gamma-aminobutyric acid type A receptor subunit rho1
- Biological Process
- Ion transport, Transport
- Molecular Function
- Chloride channel, Ion channel
- Introduction
- GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
- Gene ID
- 2569
- UniProt ID
- P24046
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COA
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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