Recombinant Anti-GP5 Vesicular Antibody, EV Displayed (VS-0425-YC43)
CAT#: VS-0425-YC43
The Recombinant Anti-GP5 Vesicular Antibody, EV Displayed (VS-0425-YC43) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GP5-expressed cells or tissues. The GP5 is part of a platelet glycoprotein system critical for adhesion and implicated in disorders like Bernard-Soulier syndrome.


Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GP5
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glycoprotein V platelet
- Biological Process
- Blood coagulation, Cell adhesion, Hemostasis
- Cellular Localization
- Cytosol
- Introduction
- Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder.
- Alternative Names
- CD42d
- Gene ID
- 2814
- UniProt ID
- P40197
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Datasheet
MSDS
COA
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See other products for "GP5"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1826z | Mouse Anti-GP5 Recombinant Antibody (clone 41B11) | WB, ELISA, IF, IHC, IP | Mouse IgG1, κ |
MOB-0507CT | Recombinant Mouse anti-Human GP5 Monoclonal antibody (DMC-TX27 (gpsnfsmz 809)) | FC, FuncS, ICC, IF | |
VS-0224-XY53 | Mouse Anti-GP5 Recombinant Antibody (VS-0224-XY53) | ELISA, FC | Mouse IgG1, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY2876 | Anti-Mouse GP5 Immunohistochemistry Kit | IHC |
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