Recombinant Anti-GRIA2 Vesicular Antibody, EV Displayed (VS-0425-YC65)
CAT#: VS-0425-YC65
The Recombinant Anti-GRIA2 Vesicular Antibody, EV Displayed (VS-0425-YC65) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GRIA2-expressed cells or tissues. The GRIA2 is a subunit of glutamate receptors, critical in neurophysiological processes sensitive to AMPA.
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GRIA2
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Rat, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glutamate ionotropic receptor AMPA type subunit 2
- Biological Process
- Ion transport, Transport
- Molecular Function
- Ion channel, Ligand-gated ion channel, Receptor
- Introduction
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+).
- Alternative Names
- GluA2, GluR-B, Glur-2, Glur2, gluR-K2
- Gene ID
- 14800
- UniProt ID
- C9K0Z1
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Downloadable Resources
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Datasheet
MSDS
COA
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