Recombinant Anti-HTR2B Vesicular Antibody, EV Displayed (VS-0425-YC428)
CAT#: VS-0425-YC428
The Recombinant Anti-HTR2B Vesicular Antibody, EV Displayed (VS-0425-YC428) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to HTR2B-expressed cells or tissues. The HTR2B is a serotonin receptor, influencing behaviors like impulsivity, with roles in cardiovascular functions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12867/if_selected.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- HTR2B
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- 5-hydroxytryptamine receptor 2B
- Biological Process
- Behavior
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Nucleoplasm
- Introduction
- This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
- Alternative Names
- 5-HT(2B), 5-HT2B
- Gene ID
- 3357
- UniProt ID
- P41595
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See other products for "HTR2B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-247 | Mouse Anti-HTR2B Recombinant Antibody (clone P2C2) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-247 | Mouse Anti-HTR2B Recombinant Antibody (clone P2C2); Fab Fragment | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-247 | Mouse Anti-HTR2B Recombinant Antibody (clone P2C2); scFv Fragment | ELISA, FC | Mouse scFv |
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