Recombinant Anti-IL13RA1 Vesicular Antibody, EV Displayed (VS-0425-YC300)
CAT#: VS-0425-YC300
The Recombinant Anti-IL13RA1 Vesicular Antibody, EV Displayed (VS-0425-YC300) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IL13RA1-expressed cells or tissues. The IL13RA1 is a subunit of the interleukin 13 receptor, forming complexes mediating signaling for immune response through JAK and STAT pathways.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1587/1858_C10_35_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000131724-IL13RA1
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IL13RA1
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interleukin 13 receptor subunit alpha 1
- Molecular Function
- Receptor
- Introduction
- The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
- Alternative Names
- CD213a1, IL-13Ra, NR4
- Gene ID
- 3597
- UniProt ID
- P78552
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1791 | Rabbit Anti-IL13RA1 Recombinant Antibody (clone DS1791AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0231CQ | Human Anti-IL13RA1 Recombinant Antibody (HPAB-0231CQ) | ELISA, FC, Inhib | Human IgG1, κ |
| HPAB-0232CQ | Human Anti-IL13RA1 Recombinant Antibody (HPAB-0232CQ) | ELISA, FC, Inhib | Human IgG1, κ |
| MRO-0830-CN | Rabbit Anti-IL13RA1 Recombinant Antibody (clone JU38-89) | WB, IF, IHC | Rabbit IgG |
| HPAB-N0144-YC | Human Anti-IL13RA1 Recombinant Antibody (clone 1A6) | ELISA, FuncS | Human IgG1 |
| VS-0723-WK221 | Rabbit Anti-IL13RA1 Recombinant Antibody (VS-0723-WK221) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0231CQ-F(E) | Human Anti-IL13RA1 Recombinant Antibody; Fab Fragment (HPAB-0231CQ-F(E)) | ELISA, FC, Inhib | Human Fab |
| HPAB-N0144-YC-F(E) | Human Anti-IL13RA1 Recombinant Antibody (clone 1A6); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-1168WJ-F(E) | Mouse Anti-IL13RA1 Recombinant Antibody (clone F997-10-1); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-1169WJ-F(E) | Mouse Anti-IL13RA1 Recombinant Antibody (clone F997-13-1); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-1170WJ-F(E) | Mouse Anti-IL13RA1 Recombinant Antibody (clone F997-20-1); Fab Fragment | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0231CQ-S(P) | Human Anti-IL13RA1 Recombinant Antibody; scFv Fragment (HPAB-0231CQ-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-0232CQ-S(P) | Human Anti-IL13RA1 Recombinant Antibody; scFv Fragment (HPAB-0232CQ-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-0233CQ-S(P) | Human Anti-IL13RA1 Recombinant Antibody; scFv Fragment (HPAB-0233CQ-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-1168WJ-S(P) | Mouse Anti-IL13RA1 Recombinant Antibody (clone F997-10-1); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-1169WJ-S(P) | Mouse Anti-IL13RA1 Recombinant Antibody (clone F997-13-1); scFv Fragment | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0901 | PE-A*02:01/Human IL13RA1 (ALPFGFILV) MHC Tetramer | FCM, IHC | |
| MHC-CN0902 | APC-A*02:01/Human IL13RA1 (ALPFGFILV) MHC Tetramer | FCM, IHC | |
| MHC-CN0903 | FITC-A*02:01/Human IL13RA1 (ALPFGFILV) MHC Tetramer | FCM, IHC | |
| MHC-CN0904 | A*02:01/Human IL13RA1 (ALPFGFILV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3485 | Anti-IL13RA1 Immunohistochemistry Kit | IHC |
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