Recombinant Anti-ITGA9 Vesicular Antibody, EV Displayed (VS-0425-YC85) (CAT#: VS-0425-YC85)
The Recombinant Anti-ITGA9 Vesicular Antibody, EV Displayed (VS-0425-YC85) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGA9-expressed cells or tissues. The ITGA9 is an alpha integrin involved in adhesion processes, with expression upregulated in small cell lung cancers.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/1430_D3_3_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/1430_D3_3_selected.jpg

Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_4_1_selected.jpg
(Immunohistochemical staining of human esophagus shows membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_4_1_selected.jpg

Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_9_3.jpg

Figure 4 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_7_5.jpg

Figure 5 Cervix
(Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_8_3.jpg
(Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_8_3.jpg

Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HEL, SH-SY5Y, SuSa, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000144668-ITGA9
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000144668-ITGA9
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGA9
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit alpha 9
- Biological Process
- Cell adhesion
- Molecular Function
- Integrin, Receptor
- Cellular Localization
- Vesicles, Nucleoplasm, Plasma membrane, Cell Junctions
- Introduction
- This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
- Alternative Names
- ALPHA-RLC, ITGA4L, RLC
- Gene ID
- 3680
- UniProt ID
- Q13797
Downloads
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ScFv Antibody Products
Fab Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-736LC | Human Anti-ITGA9 Recombinant Antibody (TAB-736LC) | ELISA | Chimeric (mouse/human) IgG |
TAB-736LC-S(P) | Mouse Anti-ITGA9 Recombinant Antibody; scFv Fragment (TAB-736LC-S(P)) | ELISA | Mouse scFv |
TAB-736LC-F(E) | Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (TAB-736LC-F(E)) | ELISA | Chimeric antibody (mouse/human) |
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For Research Use Only. Not For Clinical Use.
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