Recombinant Anti-KITLG Vesicular Antibody, EV Displayed (VS-0425-YC583) (CAT#: VS-0425-YC583)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• KITLG

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Monkey, Rat

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• KIT ligand

• Biological Process
• Cell adhesion

• Molecular Function
• Growth factor

• Cellular Localization
• Vesicles

• Introduction
• This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF

• Gene ID
• 4254

• UniProt ID
• P21583

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