Recombinant Anti-KITLG Vesicular Antibody, EV Displayed (VS-0425-YC583)
CAT#: VS-0425-YC583
The Recombinant Anti-KITLG Vesicular Antibody, EV Displayed (VS-0425-YC583) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to KITLG-expressed cells or tissues. KITLG is the ligand for the KIT receptor, important in germ cell, neural cell development, and hematopoiesis. In adults, it continues to play a pleiotropic role, mainly noted for its hematopoietic function, with two transcript variants identified.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70395/1515_E4_1_selected.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- KITLG
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Monkey, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- KIT ligand
- Biological Process
- Cell adhesion
- Molecular Function
- Growth factor
- Cellular Localization
- Vesicles
- Introduction
- This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF
- Gene ID
- 4254
- UniProt ID
- P21583
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-601 | Recombinant Anti-human KITLG Antibody | WB, IF, FuncS | IgG |
| MHH-601 | Recombinant Human Anti-human KITLG Antibody | ELISA, WB, IF, FuncS | IgG |
| MOB-1398CT | Recombinant Mouse anti-Human KITLG Monoclonal antibody (2.3_3I6-2D20) | ELISA | |
| MRO-1369-CN | Recombinant Rabbit Anti-KITLG Monoclonal Antibody (CBACN-497) | WB, IF, IHC, FC | Rabbit IgG |
| VS7-0425-WR223 | Mouse Anti-KITLG Recombinant Antibody (clone 2E1F9) | FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-601-F(E) | Recombinant Anti-human KITLG Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| MHH-601-F(E) | Recombinant Human Anti-human KITLG Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| HPAB-0299CQ-F(E) | Human Anti-KITLG Recombinant Antibody (clone A2-G8); Fab Fragment | ELISA, FC, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-601-S(P) | Recombinant Anti-human KITLG Antibody scFv Fragment | FC, Neut, Biosensors, FuncS | scFv |
| MHH-601-S(P) | Recombinant Human Anti-human KITLG Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
| HPAB-0299CQ-S(P) | Human Anti-KITLG Recombinant Antibody (clone A2-G8); scFv Fragment | ELISA, FC, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0475CL | Mouse Anti-KITLG Recombinant Antibody (TAB-0475CL) | ELISA, Block, FuncS | Mouse IgG |
| TAB-0475CL-S(P) | Mouse Anti-KITLG Recombinant Antibody; scFv Fragment (TAB-0475CL-S(P)) | ELISA, Block, FuncS | Mouse scFv |
| TAB-0475CL-F(E) | Mouse Anti-KITLG Recombinant Antibody; Fab Fragment (TAB-0475CL-F(E)) | ELISA, Block, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1949 | Hi-Affi™ Recombinant Rabbit Anti-KITLG Monoclonal Antibody (DS1949AB) | FC, ICC, IF, IHC-P, WB | IgG |
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