Recombinant Anti-LTB4R2 Vesicular Antibody, EV Displayed (VS-0425-YC257) (CAT#: VS-0425-YC257)
The Recombinant Anti-LTB4R2 Vesicular Antibody, EV Displayed (VS-0425-YC257) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LTB4R2-expressed cells or tissues. The LTB4R2 is predicted to enable receptor activity involved in signaling pathways, with roles in processes like keratinocyte migration.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72921/1501_H5_4_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72921/1501_H5_4_selected.jpg
Figure 2 IHC staining of human fallopian tube
(Immunohistochemical staining of human fallopian tube shows distinct positivity in ciliated cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/ihc_selected.jpg
(Immunohistochemical staining of human fallopian tube shows distinct positivity in ciliated cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/ihc_selected.jpg
Figure 3 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows distinct cytoplasmic positivity in superficial squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/ihc_selected.jpg
(Immunohistochemical staining of human vagina shows distinct cytoplasmic positivity in superficial squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_B_8_5.jpg
(Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_B_8_5.jpg
Figure 5 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_8_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_8_3.jpg
Figure 6 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/49119_A_9_4.jpg
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/49119_A_9_4.jpg
Figure 7 Kidney
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_9_5.jpg
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_9_5.jpg
Figure 8 Testis
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_6_6.jpg
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_6_6.jpg
Figure 9 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_7_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_7_8.jpg
Figure 10 RNA cell line category: Cell line enhanced (HaCaT)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213906-LTB4R2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213906-LTB4R2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LTB4R2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leukotriene B4 receptor 2
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Plasma membrane, Nucleoplasm
- Introduction
- Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within keratinocyte migration and signal transduction. Located in nucleoplasm and plasma membrane.
- Alternative Names
- BLT2, BLTR2, JULF2, NOP9
- Gene ID
- 56413
- UniProt ID
- Q9NPC1
Downloads
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Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1271CL | Mouse Anti-LTB4R2 Recombinant Antibody (TAB-1271CL) | FC | Mouse IgG |
| TAB-1271CL-S(P) | Mouse Anti-LTB4R2 Recombinant Antibody; scFv Fragment (TAB-1271CL-S(P)) | FC | Mouse scFv |
| TAB-1271CL-F(E) | Mouse Anti-LTB4R2 Recombinant Antibody; Fab Fragment (TAB-1271CL-F(E)) | FC | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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