Recombinant Anti-MRC2 Vesicular Antibody, EV Displayed (VS-0425-YC469)
CAT#: VS-0425-YC469
The Recombinant Anti-MRC2 Vesicular Antibody, EV Displayed (VS-0425-YC469) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MRC2-expressed cells or tissues. The MRC2 is a receptor involved in extracellular matrix remodeling and is linked to cancer metastasis.
Gene Expression
Normal Tissue
Figure 1 Gallbladder
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41991/92169_A_6_4_val_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41991/92169_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41991/92169_A_8_3.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41991/92169_A_6_6.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41991/92169_A_7_8.jpg
Normal Tissue
Figure 6 Spleen
Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41991/92169_B_8_4.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (BJ, fHDF/TERT166, HSkMC, hTERT-RPE1, U-138 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000011028-Mrc2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MRC2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Mannose receptor C type 2
- Biological Process
- Endocytosis
- Molecular Function
- Receptor
- Introduction
- This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]
- Alternative Names
- CD280, CLEC13E, ENDO180, KIAA0709
- Gene ID
- 9902
- UniProt ID
- Q9UBG0
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-008 | Recombinant Anti-mouse Mrc2 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0831CL | Mouse Anti-MRC2 Recombinant Antibody (TAB-0831CL) | ELISA | Mouse IgG |
| TAB-0830CL-S(P) | Mouse Anti-MRC2 Recombinant Antibody; scFv Fragment (TAB-0830CL-S(P)) | ELISA | Mouse scFv |
| TAB-0831CL-S(P) | Mouse Anti-MRC2 Recombinant Antibody; scFv Fragment (TAB-0831CL-S(P)) | ELISA | Mouse scFv |
| TAB-0830CL-F(E) | Mouse Anti-MRC2 Recombinant Antibody; Fab Fragment (TAB-0830CL-F(E)) | ELISA | Mouse Fab |
| TAB-0831CL-F(E) | Mouse Anti-MRC2 Recombinant Antibody; Fab Fragment (TAB-0831CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1256CT | Recombinant Mouse anti-Human MRC2 Monoclonal antibody (EML1221) | WB | |
| HPAB-M0692-YC | Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0692-YC) | WB, FuncS | Mouse IgG |
| HPAB-M0693-YC | Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0693-YC) | WB, FuncS | Mouse IgG |
| HPAB-M0694-YC | Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0694-YC) | WB, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2281 | Hi-Affi™ Recombinant Rabbit Anti-MRC2 Monoclonal Antibody (DS2281AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0692-YC-S(P) | Mouse Anti-MRC2 Recombinant Antibody; scFv Fragment (HPAB-M0692-YC-S(P)) | WB, FuncS | Mouse scFv |
| HPAB-M0693-YC-S(P) | Mouse Anti-MRC2 Recombinant Antibody; scFv Fragment (HPAB-M0693-YC-S(P)) | WB, FuncS | Mouse scFv |
| HPAB-M0694-YC-S(P) | Mouse Anti-MRC2 Recombinant Antibody; scFv Fragment (HPAB-M0694-YC-S(P)) | WB, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0692-YC-F(E) | Mouse Anti-MRC2 Recombinant Antibody; Fab Fragment (HPAB-M0692-YC-F(E)) | WB, FuncS | Mouse Fab |
| HPAB-M0693-YC-F(E) | Mouse Anti-MRC2 Recombinant Antibody; Fab Fragment (HPAB-M0693-YC-F(E)) | WB, FuncS | Mouse Fab |
| HPAB-M0694-YC-F(E) | Mouse Anti-MRC2 Recombinant Antibody; Fab Fragment (HPAB-M0694-YC-F(E)) | WB, FuncS | Mouse Fab |
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