Recombinant Anti-RCN3 Vesicular Antibody, EV Displayed (VS-0425-YC482) (CAT#: VS-0425-YC482)
The Recombinant Anti-RCN3 Vesicular Antibody, EV Displayed (VS-0425-YC482) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RCN3-expressed cells or tissues. RCN3 is involved in calcium ion binding and various processes such as ERAD, phospholipid, and surfactant homeostasis. It is localized to the endoplasmic reticulum and is expressed in the aorta, brain, and more. RCN3 is orthologous to human RCN3.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50402/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50402/if_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_7_3.jpg
Figure 3 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_8_4.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_9_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43134/97019_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (AN3-CA, ASC diff, ASC TERT1, BJ, BJ hTERT+ SV40 Large T+ RasG12V, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000142552-RCN3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000142552-RCN3
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- RCN3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Reticulocalbin 3
- Biological Process
- Protein transport, Transport
- Molecular Function
- Chaperone
- Cellular Localization
- Endoplasmic reticulum, Vesicles
- Introduction
- Predicted to enable calcium ion binding activity. Involved in several processes, including ERAD pathway; phospholipid homeostasis; and surfactant homeostasis. Located in endoplasmic reticulum. Is expressed in several structures, including aorta; brain; genitourinary system; gut gland; and trachea. Orthologous to human RCN3 (reticulocalbin 3).
- Alternative Names
- RLP49; D7Ertd671e; 6030455P07Rik; D530026G20Rik
- Gene ID
- 52377
- UniProt ID
- A0A1B0GR86
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0194-YC | Mouse Anti-RCN3 Recombinant Antibody (clone M/YC-30) | ELISA | Mouse IgG |
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