Recombinant Anti-SCN8A Vesicular Antibody, EV Displayed (VS-0425-YC53)
CAT#: VS-0425-YC53
The Recombinant Anti-SCN8A Vesicular Antibody, EV Displayed (VS-0425-YC53) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SCN8A-expressed cells or tissues. The SCN8A is a sodium channel protein crucial for neuronal action potentials, with mutations linked to cognitive disabilities.
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SCN8A
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Sodium voltage-gated channel alpha subunit 8
- Biological Process
- Ion transport, Sodium transport, Transport
- Molecular Function
- Ion channel, Sodium channel, Voltage-gated channel
- Cellular Localization
- Plasma membrane, Vesicles, Cell Junctions
- Introduction
- This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
- Alternative Names
- CerIII, CIAT, MED, NaCh6, Nav1.6, PN4
- Gene ID
- 6334
- UniProt ID
- Q9UQD0
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC53. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SCN8A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0224-FY16 | Rabbit Anti-SCN8A Polyclonal Antibody (VS-0224-FY16) | WB, IHC, ICC, IF | Rabbit IgG |
| VS-0224-FY17 | Mouse Anti-SCN8A Recombinant Antibody (VS-0224-FY17) | WB, ELISA, ICC, IF | Mouse IgG2a, κ |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, Cyt, Stim, PP, Agonist
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
-2.png)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FuncS, Inhib, IP, ELISA
-2.png)
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, WB, FC
Application: ELISA, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
