Recombinant Anti-SIRPB1 Vesicular Antibody, EV Displayed (VS-0425-YC716) (CAT#: VS-0425-YC716)

• Application
• ELISA, FC, SPR, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• SIRPB1

• Host Animal
• Rabbit

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Signal regulatory protein beta 1

• Cellular Localization
• Vesicles, Centrosome

• Introduction
• The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

• Alternative Names
• CD172b, SIRP-BETA-1

• Gene ID
• 10326

• UniProt ID
• O00241, Q5TFQ8

Select a product category from the dropdown menu below to view related products.