Recombinant Anti-SLC16A3 Vesicular Antibody, EV Displayed (VS-0425-YC51) (CAT#: VS-0425-YC51)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• SLC16A3

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Mouse, Rat

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Solute carrier family 16 member 3

• Biological Process
• Symport, Transport

• Cellular Localization
• Plasma membrane, Nuclear membrane

• Introduction
• Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]

• Alternative Names
• MCT3, MCT4

• Gene ID
• 9123

• UniProt ID
• O15427

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