Recombinant Anti-SLC16A5 Vesicular Antibody, EV Displayed (VS-0425-YC473)

CAT#: VS-0425-YC473

The Recombinant Anti-SLC16A5 Vesicular Antibody, EV Displayed (VS-0425-YC473) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC16A5-expressed cells or tissues. The SLC16A5 is a transporter for protons and substances like bumetanide, inhibited by various diuretics.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (A549, OE19, RPTEC TERT1, RT4)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • SLC16A5
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Solute carrier family 16 member 5
  • Biological Process
  • Symport, Transport
  • Introduction
  • This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
  • Alternative Names
  • MCT5, MCT6
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HPAB-M0570-YC Mouse Anti-SLC16A5 Recombinant Antibody (clone IMI4C4a) FC Mouse IgG
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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