Recombinant Anti-SLC17A6 Vesicular Antibody, EV Displayed (VS-0425-YC55)
CAT#: VS-0425-YC55
The Recombinant Anti-SLC17A6 Vesicular Antibody, EV Displayed (VS-0425-YC55) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC17A6-expressed cells or tissues. The SLC17A6 is involved in neurotransmitter transport and phosphate transport, expressed in various biological structures.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in processes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37130/165510_B_9_8_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong positivity in processes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78204/165514_B_9_8_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78204/165514_B_9_5.jpg
Normal Tissue
Figure 4 Cerebellum
Bergmann glia - cytoplasm/membrane Staining: Not detected Intensity: Negative Bergmann glia - nucleus Staining: Not detected Intensity: Negative GLUC cells - cytoplasm/membrane Staining: Not detected Intensity: Negative GLUC cells - nucleus Staining: Not detected Intensity: Negative Granular cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Granular cells - nucleus Staining: Not detected Intensity: Negative Molecular layer - neuropil Staining: Not detected Intensity: Negative Molecular layer cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Molecular layer cells - nucleus Staining: Not detected Intensity: Negative Processes in granular layer Staining: High Intensity: Strong Processes in molecular layer Staining: High Intensity: Strong Processes in white matter Staining: High Intensity: Strong Purkinje cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Purkinje cells - dendrites Staining: Not detected Intensity: Negative Purkinje cells - nucleus Staining: Not detected Intensity: Negative Synaptic glomeruli - capsule Staining: Not detected Intensity: Negative Synaptic glomeruli - core Staining: High Intensity: Strong White matter cells - cytoplasm/membrane Staining: Not detected Intensity: Negative White matter cells - nucleus Staining: Not detected Intensity: Negative
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78204/165514_B_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091664-SLC17A6
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC17A6
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Rat, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 17 member 6
- Biological Process
- Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport
- Molecular Function
- Chloride channel, Ion channel
- Introduction
- Enables L-glutamate uniporter activity; potassium:proton antiporter activity; and sodium:phosphate symporter activity. Involved in several processes, including L-glutamate transmembrane transport; hyaloid vascular plexus regression; and sodium-dependent phosphate transport. Acts upstream of or within neurotransmitter uptake. Located in synaptic vesicle. Is expressed in several structures, including cranial ganglion; nervous system; sensory organ; tail mesenchyme; and testis. Orthologous to human SLC17A6 (solute carrier family 17 member 6).
- Alternative Names
- 2900073D12Rik, DNPI, VGLUT2
- Gene ID
- 140919
- UniProt ID
- Q8BLE7
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "SLC17A6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0422-LC94 | Mouse Anti-SLC17A6 Recombinant Antibody (clone mN29/29) | ICC, WB, IF, IHC | Mouse IgG2a |
| VS-0422-LC95 | Rat Anti-SLC17A6 Recombinant Antibody (clone rtN29/29) | ICC, WB, IF, IHC | Rat IgG2b |
| VS-0422-LC96 | Human Anti-SLC17A6 Recombinant Antibody (clone hN29/29) | ICC, WB, IF, IHC | Human IgG1 |
| VS-0422-LC97 | Rabbit Anti-SLC17A6 Recombinant Antibody (clone rN29/29) | ICC, WB, IF, IHC | Rabbit IgG |
| VS-0223-WK87 | Rabbit Anti-SLC17A6 Recombinant Antibody (VS-0223-WK87) | WB, IP, ICC, IHC, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6631 | Anti-SLC17A6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6632 | Anti-Mouse SLC17A6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6633 | Anti-Rat SLC17A6 Immunohistochemistry Kit | IHC |
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