Recombinant Anti-ST8SIA1 Vesicular Antibody, EV Displayed (VS-0425-YC79) (CAT#: VS-0425-YC79)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ST8SIA1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

• Biological Process
• Lipid metabolism, Sphingolipid metabolism

• Molecular Function
• Glycosyltransferase, Transferase

• Introduction
• Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29.

• Alternative Names
• GD3S; SIAT8; SIAT8A; SIAT8-A; ST8SiaI

• Gene ID
• 6489

• UniProt ID
• Q92185

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