Recombinant Anti-SUCNR1 Vesicular Antibody, EV Displayed (VS-0425-YC390) (CAT#: VS-0425-YC390)
The Recombinant Anti-SUCNR1 Vesicular Antibody, EV Displayed (VS-0425-YC390) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SUCNR1-expressed cells or tissues. The SUCNR1 is a G protein-coupled receptor, involved in signaling pathways and located in the plasma membrane.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human adrenal gland
(Immunohistochemical staining of human adrenal gland shows strong nuclear and cytoplasmic positivity in cortical cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22745/ihc_selected.jpg
(Immunohistochemical staining of human adrenal gland shows strong nuclear and cytoplasmic positivity in cortical cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22745/ihc_selected.jpg
Figure 2 Adrenal gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22745/54368_B_4_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22745/54368_B_4_5.jpg
Figure 3 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22745/54368_A_6_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22745/54368_A_6_6.jpg
Figure 4 RNA cell line category: Group enriched (HEL, NB-4, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198829-SUCNR1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198829-SUCNR1/subcellular
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SUCNR1
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Succinate receptor 1
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human SUCNR1 (succinate receptor 1).
- Alternative Names
- Gpr91
- Gene ID
- 408199
- UniProt ID
- Q6IYF9
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Single Domain Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NBD-0081-YJ-VHH | Camelid Anti-SUCNR1 Recombinant Single Domain Antibody (NBD-0081-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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