Recombinant Anti-TMPRSS2 Vesicular Antibody, EV Displayed (VS-0425-YC89)
CAT#: VS-0425-YC89
The Recombinant Anti-TMPRSS2 Vesicular Antibody, EV Displayed (VS-0425-YC89) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TMPRSS2-expressed cells or tissues. The TMPRSS2 is a serine protease involved in physiological processes, regulated by androgenic hormones in prostate cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34493/1239_B5_1_selected.jpg
Normal Tissue
Figure 2 Colon
Endocrine cells Staining: Low Intensity: Weak Enterocytes Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes - Microvilli Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_8_3.jpg
Normal Tissue
Figure 3 Kidney
Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_8_5.jpg
Normal Tissue
Figure 4 High expression in prostate
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_2_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (CACO-2, MCF7, OE19, RT4, SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184012-TMPRSS2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TMPRSS2
- Host Animal
- Mouse
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Transmembrane serine protease 2
- Biological Process
- Host-virus interaction
- Molecular Function
- Hydrolase, Protease, Serine protease
- Cellular Localization
- Plasma membrane
- Introduction
- This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- Alternative Names
- PRSS10
- Gene ID
- 7113
- UniProt ID
- O15393
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC89. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TMPRSS2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-714CT | Mouse Anti-TMPRSS2 Recombinant Antibody (TAB-714CT) | WB, ELISA, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-715CT | Mouse Anti-TMPRSS2 Recombinant Antibody (TAB-715CT) | WB, ELISA, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-716CT | Mouse Anti-TMPRSS2 Recombinant Antibody (TAB-716CT) | WB, ELISA, FC | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-717CT | Mouse Anti-TMPRSS2 Recombinant Antibody (TAB-717CT) | WB, ELISA, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-718CT | Mouse Anti-TMPRSS2 Recombinant Antibody (TAB-718CT) | WB, ELISA, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3595 | Rabbit Anti-TMPRSS2 Recombinant Antibody (clone DS3595AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7340 | Anti-TMPRSS2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7341 | Anti-Mouse TMPRSS2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1025-YC63 | Anti-TMPRSS2 Antibody Prodrug, Protease Activated (VS-1025-YC63) | ISZ, Cyt, FuncS |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, ELISA, FuncS
Application: Neut, ELISA, Inhib, ICC, WB
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: Block, IP, IF, FC
Application: WB, ELISA, FC, IHC, IF, IP
Application: ELISA, Neut
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
