Recombinant Anti-TOMM22 Vesicular Antibody, EV Displayed (VS-0425-YC659)
CAT#: VS-0425-YC659
The Recombinant Anti-TOMM22 Vesicular Antibody, EV Displayed (VS-0425-YC659) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TOMM22-expressed cells or tissues. TOMM22 is an integral mitochondrial membrane protein forming a complex to import cytosolic preproteins, interacting with proteins like TOMM20 and TOMM40.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in renal tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/19520_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/19520_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/19520_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/19520_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/19520_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3037/19520_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100216-TOMM22/subcellular
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TOMM22
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Translocase of outer mitochondrial membrane 22
- Biological Process
- Protein transport, Translocation, Transport
- Molecular Function
- Receptor
- Cellular Localization
- Mitochondria
- Introduction
- The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.
- Alternative Names
- TOM22
- Gene ID
- 56993
- UniProt ID
- Q9NS69
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CITATIONS
RESOURCES
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Datasheet
MSDS
COA
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Lot Number:
See other products for "TOMM22"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-993 | Recombinant Anti-human TOMM22 Antibody | WB, FC, FuncS | IgG |
| MHH-993 | Recombinant Human Anti-human TOMM22 Antibody | ELISA, WB, Neut, FuncS | IgG |
| MOB-1808MZ | Recombinant Mouse Anti-Human TOMM22 Antibody | FC, ICC, IF, IHC-P, WB | Mouse antibody |
| HPAB-0044-WJ | Mouse Anti-TOMM22 Recombinant Antibody (clone HX1) | ELISA | Mouse IgG |
| ZG-0133U | Rabbit Anti-TOMM22 Recombinant Antibody (clone 7C11) | ELISA, WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-993-F(E) | Recombinant Anti-human TOMM22 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| MHH-993-F(E) | Recombinant Human Anti-human TOMM22 Antibody Fab Fragment | ELISA, FacS, FuncS | Fab |
| HPAB-0044-WJ-F(E) | Mouse Anti-TOMM22 Recombinant Antibody (clone HX1); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-993-S(P) | Recombinant Anti-human TOMM22 Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
| MHH-993-S(P) | Recombinant Human Anti-human TOMM22 Antibody scFv Fragment | Neut, IF, FuncS | scFv |
| HPAB-0044-WJ-S(P) | Mouse Anti-TOMM22 Recombinant Antibody (clone HX1); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3637 | Rabbit Anti-TOMM22 Recombinant Antibody (clone DS3637AB) | WB, IHC-P, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7422 | Anti-TOMM22 Immunohistochemistry Kit | IHC |
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