Recombinant Anti-UPK1B Vesicular Antibody, EV Displayed (VS-0425-YC199)
CAT#: VS-0425-YC199
The Recombinant Anti-UPK1B Vesicular Antibody, EV Displayed (VS-0425-YC199) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to UPK1B-expressed cells or tissues. The UPK1B is a protein from the transmembrane 4 superfamily, expressed on cell surfaces influencing cell development and growth. It plays a role in bladder epithelial physiology, possibly stabilizing the apical membrane.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31799/68903_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31799/68903_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31799/68903_A_7_5.jpg
Normal Tissue
Figure 4 Urinary bladder
Urothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31799/68903_A_6_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31799/68903_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (A549, CACO-2, RPTEC TERT1, RT4)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000114638-UPK1B
❮
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Recombinant Antibody
- Application
- Cyt, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- UPK1B
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Uroplakin 1B
- Introduction
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.
- Alternative Names
- TSPAN20, UPK1
- Gene ID
- 7348
- UniProt ID
- O75841
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Datasheet
MSDS
COA
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See other products for "UPK1B"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-240CQ | Anti-Human UPK1B Recombinant Antibody (1G9) | Cyt, ELISA, FC | |
| TAB-241CQ | Anti-Human UPK1B Recombinant Antibody (5H9) | Cyt, ELISA, FC | |
| TAB-240CQ-S(P) | Anti-Human UPK1B Recombinant Antibody scFv Fragment (1G9) | ELISA, WB, IHC | |
| TAB-240CQ-F(E) | Anti-Human UPK1B Recombinant Antibody Fab Fragment (1G9) | ELISA, WB, IHC | |
| TAB-241CQ-F(E) | Anti-Human UPK1B Recombinant Antibody Fab Fragment (5H9) | ELISA, WB, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-242CQ | Anti-Human UPK1B Recombinant Antibody (ch1G9) | Cyt, ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-242CQ-S(P) | Anti-Human UPK1B Recombinant Antibody scFv Fragment (ch1G9) | ELISA, WB, IHC | Chimeric antibody (mouse/human) |
| TAB-243CQ-S(P) | Anti-Human UPK1B Recombinant Antibody scFv Fragment (ch5H9) | ELISA, WB, IHC | Chimeric antibody (mouse/human) |
| TAB-242CQ-F(E) | Anti-Human UPK1B Recombinant Antibody Fab Fragment (ch1G9) | ELISA, WB, IHC | Chimeric antibody (mouse/human) |
| TAB-243CQ-F(E) | Anti-Human UPK1B Recombinant Antibody Fab Fragment (ch5H9) | ELISA, WB, IHC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3794 | Rabbit Anti-UPK1B Recombinant Antibody (clone DS3794AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0250-YC | Human Anti-UPK1B Recombinant Antibody (clone chSC115.9) | FuncS | Chimeric (mouse/human) IgG |
| HPAB-J0251-YC | Human Anti-UPK1B Recombinant Antibody (clone hSC115.9) | FuncS | Humanized (mouse/human) IgG, κ |
| HPAB-J0252-YC | Human Anti-UPK1B Recombinant Antibody (clone chSC115.18) | FuncS | Chimeric (mouse/human) IgG |
| HPAB-J0253-YC | Human Anti-UPK1B Recombinant Antibody (clone hSC115.18 mut6) | FC | Humanized (mouse/human) IgG, κ |
| HPAB-J0254-YC | Mouse Anti-UPK1B Recombinant Antibody (clone SC115.7) | IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0250-YC-S(P) | Human Anti-UPK1B Recombinant Antibody (clone chSC115.9); scFv Fragment | FC, FuncS | Mouse scFv |
| HPAB-J0251-YC-S(P) | Human Anti-UPK1B Recombinant Antibody (clone hSC115.9); scFv Fragment | FC | Humanized (mouse/human) scFv |
| HPAB-J0252-YC-S(P) | Human Anti-UPK1B Recombinant Antibody (clone chSC115.18); scFv Fragment | FC | Mouse scFv |
| HPAB-J0253-YC-S(P) | Human Anti-UPK1B Recombinant Antibody (clone hSC115.18 mut6); scFv Fragment | FC | Humanized (mouse/human) scFv |
| HPAB-J0254-YC-S(P) | Mouse Anti-UPK1B Recombinant Antibody (clone SC115.7); scFv Fragment | IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0250-YC-F(E) | Human Anti-UPK1B Recombinant Antibody (clone chSC115.9); Fab Fragment | FC, FuncS | Chimeric (mouse/human) Fab |
| HPAB-J0251-YC-F(E) | Human Anti-UPK1B Recombinant Antibody (clone hSC115.9); Fab Fragment | FC | Humanized (mouse/human) Fab |
| HPAB-J0252-YC-F(E) | Human Anti-UPK1B Recombinant Antibody (clone chSC115.18); Fab Fragment | FC | Chimeric (mouse/human) Fab |
| HPAB-J0258-YC-F(E) | Mouse Anti-UPK1B Recombinant Antibody (clone SC115.1); Fab Fragment | FC | Mouse Fab |
| HPAB-J0259-YC-F(E) | Mouse Anti-UPK1B Recombinant Antibody (clone SC115.40); Fab Fragment | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7756 | Anti-UPK1B Immunohistochemistry Kit | IHC |
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