Recombinant Anti-VAMP1 Vesicular Antibody, EV Displayed (VS-0425-YC708)
CAT#: VS-0425-YC708
The Recombinant Anti-VAMP1 Vesicular Antibody, EV Displayed (VS-0425-YC708) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VAMP1-expressed cells or tissues. VAMP1 is a synaptobrevin family member involved in synaptic vesicle docking, linked to spastic ataxia, with various transcript variants.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16119/35787_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16119/35787_A_8_3.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16119/35787_A_9_4.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16119/35787_A_6_6.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16119/35787_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139190-VAMP1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- VAMP1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Cat, Pig, Salamander
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Vesicle associated membrane protein 1
- Introduction
- Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
- Alternative Names
- SYB1, VAMP-1
- Gene ID
- 6843
- UniProt ID
- P23763
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Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "VAMP1"
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| MOB-2196CT | Recombinant Mouse anti-Human VAMP1 Monoclonal antibody (EML1653) | WB |
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| MOR-3816 | Rabbit Anti-VAMP1 Recombinant Antibody (clone DS3816AB) | WB, IHC-P, ICC, IF | Rabbit IgG |
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| MRO-1569-CN | Rabbit Anti-VAMP1 Recombinant Antibody (clone JG40-19) | WB, IHC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7795 | Anti-VAMP1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7796 | Anti-Mouse VAMP1 Immunohistochemistry Kit | IHC |
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