Recombinant Anti-VIPR1 Vesicular Antibody, EV Displayed (VS-0425-YC171)
CAT#: VS-0425-YC171
The Recombinant Anti-VIPR1 Vesicular Antibody, EV Displayed (VS-0425-YC171) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VIPR1-expressed cells or tissues. The VIPR1 is a receptor for vasoactive intestinal peptide, involved in processes such as smooth muscle relaxation and water and ion flux regulation, with several transcript variants found.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26777/60860_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26777/60860_A_8_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26777/60860_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26777/60860_A_6_6.jpg
Normal Tissue
Figure 5 Skeletal muscle
Myocytes
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26777/60860_B_3_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26777/60860_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, OE19, RT4, SK-BR-3, WM-115)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, OE19, RT4, SK-BR-3, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000114812-VIPR1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- VIPR1
- Host Animal
- Human
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Vasoactive intestinal peptide receptor 1
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- HVR1, RDC1, VPAC1, VPAC1R
- Gene ID
- 7433
- UniProt ID
- P32241
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "VIPR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1197z | Mouse Anti-VIPR1 Recombinant Antibody (clone 18B11) | WB, IP, IF, IHC, ELISA | Mouse IgG2a, κ |
| MOB-2219CT | Recombinant Mouse anti-Human VIPR1 Monoclonal antibody (BT69) | FC, IHC, WB | |
| VS13-YC1217 | Rabbit Anti-VIPR1 Recombinant Antibody (VS13-YC1217) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-358CQ | Anti-Human VIPR1 Recombinant Antibody (23A11) | Inhib, FC, Neut | |
| TAB-358CQ-S(P) | Anti-Human VIPR1 Recombinant Antibody scFv Fragment (23A11) | ELISA, FC, WB, Neut | |
| TAB-358CQ-F(E) | Anti-Human VIPR1 Recombinant Antibody Fab Fragment (23A11) | ELISA, FC, WB, Neut |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-359CQ | Anti-Human VIPR1 Recombinant Antibody (hu23A11) | FC, FuncS | Humanized antibody |
| TAB-359CQ-S(P) | Anti-Human VIPR1 Recombinant Antibody scFv Fragment (hu23A11) | ELISA, FC, WB, Neut | Humanized antibody |
| TAB-359CQ-F(E) | Anti-Human VIPR1 Recombinant Antibody Fab Fragment (hu23A11) | ELISA, FC, WB, Neut | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3840 | Rabbit Anti-VIPR1 Recombinant Antibody (clone DS3840AB) | FC, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7858 | Anti-VIPR1 Immunohistochemistry Kit | IHC |
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