Recombinant Anti-VIPR1 Vesicular Antibody, EV Displayed (VS-0425-YC171) (CAT#: VS-0425-YC171)

The Recombinant Anti-VIPR1 Vesicular Antibody, EV Displayed (VS-0425-YC171) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VIPR1-expressed cells or tissues. The VIPR1 is a receptor for vasoactive intestinal peptide, involved in processes such as smooth muscle relaxation and water and ion flux regulation, with several transcript variants found.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • VIPR1
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG1 kappa
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Vasoactive intestinal peptide receptor 1
  • Molecular Function
  • G-protein coupled receptor, Receptor, Transducer
  • Introduction
  • This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • HVR1, RDC1, VPAC1, VPAC1R

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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