Recombinant Protein A Agarose (VS-0824-WK6) (CAT#: VS-0824-WK6)

This recombinant Protein A agarose is a genetically engineered form of Protein A that is produced from a nonpathogenic strain of Bacillus. Although some non-essential regions have been removed, the recombinant is similar to native Protein A in size and IgG-binding sites. The protein has four high affinity binding sites capable of specifically binding to the Fc region of immunoglobulin molecules from several species. Protein A is heat-stable and retains its native conformation even when exposed to denaturing reagents such as 4M urea, 4M thiourea and 6M guanidine hydrochloride. This Recombinant Protein A Agaroseis prepared using a coupling method that results in excellent resin stability and binding characteristics. The special Protein A buffers enhance IgG binding, resulting in higher yields compared with conventional methods.