Strain Construction and Screening Service
As part of our Strains & Strain Bank Establishment services, our Strain Construction and Screening Service is designed to provide clients with the ability to construct, optimize, and identify high-performing microbial or cell strains tailored for specific applications. Whether you're developing production strains for biopharmaceuticals, industrial enzymes, or other biotechnology products, we offer comprehensive solutions for strain development, screening, and optimization. Our team of experienced scientists combines cutting-edge technology with years of expertise to create reliable, robust strains that meet the highest standards of genetic and phenotypic performance.
Strain Construction and Screening Service at Creative Biolabs
Strain construction is a critical component of many biotechnology processes, and the creation of stable, high-yielding strains requires a deep understanding of genetics, microbiology, and fermentation. Our service enables the development of custom strains through advanced genetic engineering techniques, followed by thorough screening to identify the most promising candidates. We provide solutions for a variety of organisms, including bacteria, yeast, fungi, and mammalian cells, addressing both small-scale research needs and large-scale production environments.
Fig.1 Different organisms.1
- Service Contents
Strain Design and Construction
We leverage advanced techniques in synthetic biology to engineer and construct strains with desired traits. This may involve genetic modifications to enhance yield, resistance, or functionality.
High-Throughput
Screening
Screening
Following strain construction, we employ high-throughput screening methods to rapidly evaluate the performance and characteristics of engineered strains in various conditions.
Phenotypic and Genotypic Characterization
We assess the stability and functionality of constructed strains through both phenotypic assays and genotypic analysis, ensuring that they meet performance criteria.
Scale-Up and
Optimization
Optimization
For the most promising strains, we provide scale-up services to test and optimize production conditions in bioreactor systems.
- Service Workflow
- Technical Expertise
Our Strain Construction and Screening Service employs a variety of advanced techniques to ensure successful strain development:
- Plasmid-Based Transformation: We use plasmid-based transformation methods for introducing genetic material into strains, ensuring stable integration and expression of desired traits.
- Next-Generation Sequencing (NGS): To verify the success of strain construction and monitor genetic integrity, we utilize NGS technologies for comprehensive genomic analysis.
- Automated Screening Systems: High-throughput screening platforms allow us to test large numbers of strains efficiently and identify optimal candidates quickly.
- Metabolic Engineering: Using metabolic engineering strategies, we can optimize the production of biofuels, pharmaceuticals, or other metabolites by modifying the strain's metabolic pathways.
Why Choose Us
Customized Solutions
Our service is fully customizable, allowing clients to create strains tailored to their specific needs, whether for basic research or industrial applications.
Expert Team
Our interdisciplinary team brings a wealth of expertise in strain construction, molecular biology, and metabolic engineering, ensuring high-quality outcomes.
Rapid Turnaround
Leveraging high-throughput technologies enables us to conduct strain screening efficiently, significantly reducing the time from strain design to evaluation.
Rigorous Quality Control
We implement strict quality control measures at each step of the process to guarantee the performance and stability of the constructed strains.
Contact Us
At Creative Biolabs, our Strain Construction and Screening Service offers a unique blend of expert knowledge and advanced technologies designed to meet the specific needs of our clients in biotechnology and research. Our dedication to quality and creativity guarantees that we will provide premium, tailored strains that will improve your R&D initiatives. By partnering with us, you gain access to a team of dedicated professionals ready to support your goals through every stage of strain construction and analysis. Contact us today to discuss how we can assist you in your strain development initiatives.
Reference
- Ding, Qiang, and Chao Ye. "Microbial cell factories based on filamentous bacteria, yeasts, and fungi." Microbial cell factories vol. 22,1 20. 30 Jan. Distributed under Open Access license CC BY 4.0, without modification.
For research use only. Not intended for any clinical use.
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