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β-lactamases
Anti-β-lactamases Recombinant Antibody Products
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- Derivation: Phage Display Library
- Type: Dromedary VHH
- Application: ELISA
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- Derivation: Phage Display Library
- Type: Dromedary VHH
- Application: ELISA
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- Derivation: Llama
- Species Reactivity: B. licheniformis
- Type: Llama VHH
- Application: WB, FuncS
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- Derivation: Llama
- Species Reactivity: B. licheniformis
- Type: Llama VHH
- Application: FACS, ELISA, FuncS
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For Research Use Only. Not For Clinical Use.
Beta-lactamases are enzymes produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the enzyme lactamase breaks the β-lactam ring open, deactivating the molecule's antibacterial properties.