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Anti-AADAC Recombinant Antibody Products

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Anti-AADAC Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is your pharmacology and drug metabolism expert. We provide only the highest quality anti-Arylacetamide Deacetylase (AADAC) recombinant antibodies for your research needs. AADAC is an important drug-metabolizing enzyme that is involved in the efficacy and toxicity of several drugs. Creative Biolabs recombinant antibodies are a critical part of pharmacokinetic analysis, drug development, and personalized medicine research studies.

AADAC: A Key Hydrolase in Drug Metabolism

AADAC is an important hydrolase enzyme that is expressed in the endoplasmic reticulum in the liver and intestine. This important drug-metabolizing enzyme inactivates a large number of drugs and xenobiotics by metabolizing the ester or amide linkage in the substrate molecule. Arylacetamide deacetylase is required for inactivation of both the active metabolite of the chemotherapeutic agent irinotecan (SN-38) and the anti-androgen flutamide. AADAC genetic variability and the resulting changes in drug clearance can have a major impact on both therapeutic effectiveness and the potential for adverse events in individuals. The proper study of AADAC will allow for more optimized drug design and applications.

Alternative Names

AADAC; Human AADAC

Background

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Group enriched (Hepatocytes, Proximal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (A549, ASC diff, EFO-21, HBEC3-KT)

Molecular function

Hydrolase

More Types Infomation

Anti-AADAC rAb Products

Creative Biolabs' anti-AADAC recombinant antibodies are highly specific, reproducible, and optimized for robust performance. Our antibodies are also thoroughly validated to detect the presence of AADAC enzyme in liver microsomes and other tissues. Optimized for Western Blot and IHC assays, these rAbs are dependable for the highest quality research to provide a clear picture of drug metabolism and genetic variability.

Table 1. Featured anti-AADAC recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
MOB-0519MZ Mouse Anti-AADAC Recombinant Antibody (clone CBLS-063) Human Mouse IgG2b WB

Customer Reviews

Excellent
Ch**e
Mouse Anti-AADAC Recombinant Antibody (clone CBLS-063)
I was able to find the right antibody for our research on the metabolism of the chemotherapeutic agent irinotecan. The antibody cleanly detected the expected band in human liver microsomes on Western blot.
22/Nov/2023

rAb Production

Creative Biolabs takes the specialized field of drug metabolism research to the next level by using the most advanced production platforms. Our anti-AADAC recombinant antibodies are produced in an expression system that has been optimized for the best results to ensure that your antibody will specifically recognize the native, membrane-associated enzyme. This advanced process will ensure the most specific and active antibody possible for your research.

Featured Anti-AADAC Recombinant Antibody Production PlatformsMilligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-AADAC recombinant antibody production.

Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-AADAC recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to fueling scientific innovation by providing a flexible, full suite of antibody modalities to fit the needs of your research. Our anti-AADAC recombinant antibodies are available in a number of modalities and are customizable to fit the needs of your research to support drug metabolism and drug design study needs worldwide.

AADAC antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-AADAC recombinant antibody production and modalities.

Explore the importance of AADAC with Creative Biolabs' recombinant antibodies. Our portfolio of anti-AADAC antibodies has the highest specificity and is thoroughly validated to be the perfect reagent for your drug development and personalized medicine research. Trust us for superior quality and service to power discovery. Talk to our experts today.

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