AARSD1

AARSD1 belongs to the class-II aminoacyl-tRNA synthetasefamily, Alax-L subfamily. AARSD1 binds 1 zinc ionper subunit functions in trans to edit the amino acid moiety from incorrectlycharged tRNA(Ala). Four transcript variants havebeen described for AARSD1: NM_025267.3, NM_001136042.2, NM_001142653.1 andNM_001142654.1. It has been determined that the latter two variants represent adistinct upstream locus, which is now represented by GeneID:100885848(PTGES3L), while the former two variants represent readthrough transcripts between PTGES3L and thislocus (AARSD1). The readthrough locus (PTGES3L-AARSD1) is nowrepresented by GeneID:100885850.