Anti-ACAA2 Recombinant Antibody Products

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Anti-ACAA2 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs delivers high-performance recombinant antibodies against ACAA2, designed to advance biomedical investigations. Utilizing state-of-the-art technological platforms, we ensure consistent product quality and dependable results. Our diverse antibody lineup demonstrates our commitment to accelerating scientific discovery and providing measurable research value. Beyond superior reagents, we offer end-to-end technical assistance to support researchers throughout their workflows. Choosing Creative Biolabs means gaining access to forward-thinking tools and a trusted partner dedicated to your scientific success.

ACAA2: A Crucial target in Autoimmune Disorders and Inflammatory Diseases

ACAA2 plays a critical role in human disease pathogenesis through its essential function in fatty acid β-oxidation. This mitochondrial enzyme's dysfunction disrupts lipid metabolism homeostasis, leading to severe metabolic disorders characterized by the accumulation of toxic fatty acid intermediates. Impaired activity has been linked to various neurodegenerative conditions, likely due to energy deficits and oxidative stress resulting from defective mitochondrial energetics. The protein's involvement in peroxisome proliferator-activated receptor signaling pathways connects its dysregulation to insulin resistance and type 2 diabetes mellitus. In cancer biology, altered expression patterns have been observed in multiple malignancies, where metabolic reprogramming favors tumor growth and survival. Genetic mutations affecting this thiolase cause rare inborn errors of metabolism presenting with developmental delays, cardiomyopathy, and hepatic dysfunction. Structural studies reveal unique substrate-binding characteristics that could be targeted for therapeutic intervention in metabolic diseases. The enzyme's dual role in both fatty acid catabolism and ketone body metabolism suggests broader implications for neurological and cardiovascular disorders. Current research explores its potential as a biomarker for metabolic syndrome progression and as a therapeutic target for rare lipid storage diseases, while addressing challenges in developing tissue-specific modulators of its complex enzymatic activity.

Alternative Names

Complement Acetyl-CoA Acyltransferase 2; Mitochondrial 3-Oxoacyl-Coenzyme A Thiolase; Mitochondrial 3-Oxoacyl-CoA Thiolase; Acetyl-Coenzyme A Acyltransferase 2; EC 2.3.1.16; T1; 3-Ketoacyl-CoA Thiolase, Mitochondrial

Background

The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.

Anti-ACAA2 rAb Products

We aim to drive scientific progress by offering recombinant anti-ACAA2 antibodies characterized by outstanding quality, cost-effective solutions, and reliable expert support.

Table 1. Featured anti-ACAA2 recombinant antibody products at Creative Biolabs.

Customer Reviews

Excellent

E**tt
Mouse Anti-ACAA2 Recombinant Antibody (clone CBLS-009) (CAT#: MOB-0404MZ)

We used the Mouse Anti-ACAA2 Recombinant Antibody for Western blot analysis on human liver tissue samples. The antibody showed specific and clear bands with minimal background noise. It was easy to handle and produced consistent results across multiple experiments. Overall, it performed reliably for detecting ACAA2 in our samples without any issues.

15/Feb/2024

Excellent

Gr**n
Rabbit Anti-ACAA2 Recombinant Antibody (clone R35-1Y-2) (CAT#: VS3-FY2145)

In our immunofluorescence studies, the Rabbit Anti-ACAA2 Recombinant Antibody was tested on mouse muscle cells. The antibody provided distinct and specific staining with low background interference. It was straightforward to use and delivered reproducible results across different runs. This antibody proved to be a dependable tool for visualizing ACAA2 in IF applications.

06/Apr/2023

Excellent

N**an
Rabbit Anti-ACAA2 Recombinant Antibody (clone 12F4) (CAT#: VS4-WK4)

We evaluated the Rabbit Anti-ACAA2 Recombinant Antibody using ELISA on human plasma samples. The antibody showed strong specificity and consistent sensitivity throughout our tests. It was easy to incorporate into our assay protocol and delivered reliable results with minimal variation. Overall, this antibody is a solid choice for ELISA-based detection of ACAA2 in biological samples.

20/Oct/2023

rAb Production

Drawing on our deep expertise in recombinant antibody development, we provide reliable, top-grade products alongside responsive support, ensuring efficient delivery while maintaining rigorous quality benchmarks.

Featured Anti-ACAA2 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale recombinant antibody production.

Fig.2 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs offers researchers a diverse range of cutting-edge recombinant antibodies available in various formats. With extensive proficiency in antibody engineering, we also provide tailored customization services to align with the specific objectives of your scientific projects.

Fig.3 Full Length Anti-ACAA2 Recombinant Antibody Production and Modalities.

If you need further details about the ACAA2 target, please don't hesitate to contact us by phone or email. Our experienced team is ready to help with any questions or issues you may encounter during your research, providing the support necessary for successful experiments.