Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Late spermatids)
Low immune cell specificity
Low cell line specificity
Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Forms heterodimers with POT1. Identified in a complex with POT1 and single-stranded telomeric DNA. Interacts with STN1 and TINF2.
DNA-binding
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For Research Use Only. Not For Clinical Use.