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ACTR2
Loading...Anti-ACTR2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Anti-ACTR2 Immunohistochemistry Kit (VS-0325-XY35)
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- Species Reactivity: Human, Mouse, Rat
- Target: ACTR2
- Application: IHC
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- Anti-Mouse ACTR2 Immunohistochemistry Kit (VS-0525-XY129)
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- Species Reactivity: Human, Mouse, Rat
- Target: ACTR2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the Arp2/3 complex composed of ACTR2/ARP2, ACTR3/ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with AVIL (PubMed:29058690).
Molecular function
Actin-binding
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