Anti-ACTR2 Recombinant Antibody Products

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Anti-ACTR2 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs delivers advanced recombinant antibodies against ACTR2 to support cutting-edge biomedical research across diverse fields. Through the integration of next-generation production technologies and meticulous quality assurance, we provide reagents that consistently meet demanding performance expectations. Our broad and carefully developed antibody portfolio is designed to offer researchers high-value solutions that ensure both accuracy and reproducibility in experimental workflows. In addition to top-tier antibody products, we are proud to offer expert technical assistance to help guide users through every phase of their research. By partnering with Creative Biolabs, you benefit not only from innovative scientific tools but also from a team deeply committed to facilitating your research objectives with accuracy and reliability.

ACTR2: A Central Regulator in Cancer Immunity and Neurodevelopmental Disorders

ACTR2 encodes a core component of the Arp2/3 complex, which is essential for actin filament nucleation and remodeling—key processes involved in maintaining cell shape, migration, and intracellular transport. Disruption of this gene's function has been associated with a variety of pathological conditions, particularly those involving cytoskeletal abnormalities and altered cell dynamics. In cancer, aberrant expression has been linked to enhanced cell motility and invasion, contributing to tumor progression and metastasis by facilitating changes in the actin cytoskeleton and cell–extracellular matrix interactions. Its involvement in immune regulation has also drawn attention, as improper cytoskeletal organization can impair immune cell activation, migration, and phagocytosis, potentially affecting responses to infection and inflammation. Additionally, variants affecting the gene's function have been observed in developmental disorders characterized by neurological deficits, suggesting a role in neurodevelopmental processes where precise control of cell structure and movement is required. In cardiovascular disease, altered actin dynamics may contribute to vascular remodeling and smooth muscle cell dysfunction. As research continues, this cytoskeletal regulator emerges as a potential therapeutic target in diseases marked by disrupted cell architecture, signaling, and migration, underscoring its broad biomedical relevance across both malignant and non-malignant conditions.

Alternative Names

Complement ACTR2; ARP2 Actin-Related Protein 2 Homolog (Yeast); ARP2; ARP2 (Actin-Related Protein 2, Yeast) Homolog; Actin-Like Protein 2; Actin-Related Protein 2

Background

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.

Anti-ACTR2 rAb Products

We are dedicated to accelerating research and discovery by providing our premium anti-ACTR2 recombinant antibody products that combine the highest quality, exceptional value, and comprehensive top-tier technical support.

Customer Reviews

Excellent

Ra**z
Mouse Anti-ACTR2 Recombinant Antibody (clone 19B7) (CAT#: MOB-3098z)

We used the Mouse Anti-ACTR2 Recombinant Antibody in ELISA assays with lysates from HEK293 cells. The antibody showed strong and specific binding, with minimal background interference. It performed consistently across several batches, which gave us confidence in its reliability. The signal was clean and reproducible, and the protocol didn't require much adjustment. Overall, it's a solid reagent for detecting this target in routine ELISA setups.

12/Feb/2024

Excellent

P**ce
Recombinant Rabbit Anti-ACTR2 Antibody (clone R04-3H3) (CAT#: VS3-FY36)

I tested the Recombinant Rabbit Anti-ACTR2 in WB and IF using HeLa and HEK293T lysates. It worked well in WB, detecting a clear band at the expected size. In IF, the signal was clean in fixed cells, though some background appeared when overexposed. The antibody didn't perform well in ICC with my primary neurons—weak staining despite optimization. Overall, reliable for WB and IF in common cell lines, but may need titration for sensitive applications.

18/Apr/2023

rAb Production

Over the years, we have built up extensive expertise in the production and optimization of recombinant antibodies. By offering top-tier services, we are able to deliver recombinant antibody products that meet superior quality standards and high benchmarks within the shortest possible time frame. This commitment to excellence allows us to ensure that our clients receive the best possible products and support for their research needs.

Featured Anti-ACTR2 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-ACTR2 recombinant antibody production.

Fig.2 Gram-scale anti-ACTR2 recombinant antibody production.

rAb Modalities

Creative Biolabs is devoted to providing researchers with the most comprehensive and cutting-edge high-quality recombinant antibodies across diverse formats. Our expertise in recombinant antibody technologies spans a broad spectrum of advanced engineering methodologies, and our products are supported by exceptional custom engineering services meticulously designed to align with your unique research requirements.

Fig.3 Full Length Anti-ACTR2 Recombinant Antibody Production and Modalities.

If you have any further questions about ACTR2 or need experimental guidance, please don't hesitate to contact us by phone or email. Our technical support team is ready to help with troubleshooting, protocol optimization, or application-specific advice—whether you're using WB, IF, ICC, or other techniques. We're committed to providing the assistance you need to achieve reliable results, so reach out anytime for personalized support. Your research success is our priority, and we're here to help every step of the way.