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ADAM23
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- Chicken Anti-ADAM23 Polyclonal IgY (BRD-0022MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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- Chicken Anti-ADAM23 Polyclonal IgY (BRD-1055MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Anti-ADAM23 Immunohistochemistry Kit (VS-0525-XY150)
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- Species Reactivity: Human
- Target: ADAM23
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Group enriched (Excitatory neurons, Inhibitory neurons, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enriched (memory CD4 T-cell)
Cell line specificity
Cell line enhanced (hTERT-RPE1, RH-30, RPMI-8226)
Interaction
Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3.
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