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ADD1

Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Rod photoreceptor cells, Cone photoreceptor cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit.

Molecular function

Actin-binding, Calmodulin-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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