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ADRA2B
This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014]
Protein class
Disease related genes, FDA approved drug targets, G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Sertoli cells, Smooth muscle cells, Glandular and luminal cells, Langerhans cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, EFO-21)
Interaction
Interacts with RAB26 (PubMed:23105096). Interacts with PPP1R9B (PubMed:24114805). Interacts with GGA1, GGA2 and GGA3 (PubMed:27901063, PubMed:26811329).
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
-
- Species Reactivity: Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
- Chicken Anti-α-2B Adrenergic Receptor Polyclonal IgY (BRD-0028MZ)
-
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.